Developing a public repository for EurOPDX models

In collaboration with the Elemento lab at Weill Cornell Medical College and the Schultz lab at the Memorial Sloan Kettering Cancer Center (New York, NY, USA) we deployed an instance of the cBioPortal dedicated to EurOPDX (europdx.eu) data visualisation.

The cBioPortal allows users an exploration of multidimensional cancer genomic data (http://www.cbioportal.org/). In this pilot stage of the EurOPDX cBioPortal (available at https://cbio.cerit-sc.cz/) are 5 colorectal or breast cancer patient derived xenografts (PDX) models cohorts (or "studies") from 4 laboratories of the consortium included. It is our aim to gradually include PDX data from the whole consortium as they will be available. Now it is possible to browse DNA copy-number data, mRNA expression data and mutation data from PDX models.

This work was supported by the project GAMU: EDIRex (EU H2020 RI) preparation phase; EU H2020: EDIREX

 

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